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About GELCLAIR
GELCLAIR has a mechanical action indicated for the
management of pain and relief of pain by adhering to the
mucosal surface of the mouth, soothing oral lesions of
various etiologies, including oral mucositis/stomatitis (may
be caused by chemotherapy or radiation therapy).
Key ingredients in GELCLAIR combine to protect, hydrate, and
soothe the oral mucosa, providing relief from pain:
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Polyvinylpyrrolidone (PVP) protects the mucosa |
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Hyaluronic acid
(sodium hyaluronate) hydrates and soothes the
mucosa |
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Glycyrrhetinic
acid (licorice root extract) is a mild flavoring
agent gentle on the mucosa |
GELCLAIR coats the exposed nerve endings of the mucosa
throughout the phases of oral mucositis.
GELCLAIR
provides rapid and durable pain relief
Study results show that GELCLAIR significantly reduces oral
mucositis pain for 5 to 7 hours after administration.2
Short-term
results
In an open label study,* 30 patients experienced a 92%
reduction in mean overall oral pain associated with lesions
of the mouth and oropharynx 5 to 7 hours after treatment
(p<0.005).2
GELCLAIR helps restore the ability
to eat and drink more normally.2
Medium-term
results
In the same open label study, 87% of patients reported
reduced pain associated with swallowing foods, liquids, and
saliva after 7 days of use (p<0.005).2
GELCLAIR helped reduce pain associated with eating and
drinking.2
Safety
Profile
GELCLAIR has a favorable safety profile1:
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Generally
well-tolerated |
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No known drug
interactions |
No adverse events have been reported in clinical trials with
the use of GELCLAIR. Postmarketing reports have included
infrequent complaints of a burning sensation in the mouth.
For Package Insert,
click here.
*Open-label study of 30 patients with painful lesions of the
mouth and oropharynx associated with chemotherapy,
radiation, mucositis, HIV disease, severe diffuse aphthous
ulcers, or oral surgery. Pain was scored on a Visual
Numerical Scale ranging from 0 (no pain) to 10 (worst pain,
with scores recorded at baseline and at 5 to 7 hours after
treatment. GELCLAIR was administered TID.2,8 |
