GELCLAIR® was approved by the FDA in 2001 and is specifically designed and approved for management and relief of pain in oral mucositis. It contains key ingredients that protect, hydrate and soothe the mouth and has a mild flavor. Download Gelclair Patient Brochure: GELCLAIR® was approved by the FDA in 2001 and is specifically designed and approved for management and relief of pain in oral mucositis. It contains key ingredients that protect, hydrate and soothe the mouth and has a mild flavor.
 
If you are receiving chemotherapy or radiation to the head and/or neck, you are at risk for oral mucositis. People who smoke, drink alcohol, don’t practice daily oral care, wear ill-fitting braces or dentures, and/or have dry mouth while receiving chemotherapy or radiation are at greater risk for oral mucositis Indications  
 

About GELCLAIR®  

GELCLAIR® has a mechanical action indicated for the management of pain and relief of pain by adhering to the mucosal surface of the mouth, soothing oral lesions of various etiologies, including oral mucositis/stomatitis. It is a concentrated oral gel available in single use packets of 15 ml each.

GELCLAIR® bioadherent oral gel helps patients who are undergoing radiation or chemotherapy (or a combination of the two) by relieving the pain of oral mucositis. GELCLAIR® is composed of three key ingredients that combine to provide pain relief to the mucosal surface of the mouth:

  • Polyvinylpyrrolidone (PVP) protects the mucosa

  • Hyaluronic acid (sodium hyaluronate) hydrates and soothes the mucosa

  • Glycyrrhetinic acid (licorice root extract) is a mild flavoring agent gentle on the mucosa

    GELCLAIR® is designed to be

    • Non-numbing

    • Non-stinging

    • Non-drying

    Adapted from Cawley

    GELCLAIR® coats the exposed nerve endings of the mucosa throughout the phases of oral mucositis

     

GELCLAIR® provides rapid and durable pain relief. Study results show that GELCLAIR® significantly reduces oral mucositis pain for 5 to 7 hours after administration.11

Short-Term results

In an open label study 30 patients experienced a 92% reduction in mean overall oral pain associated with lesions of the mouth and oropharyx 5 to 7 hours after treatment (p<0.005)11,12

Gelclair for: Mouth sores, Mouth ulcers, Chemotherapy side effects, Stomatitis, Magic mouthwash, Mucositis, mouth treatment ulcer, mouth lesions, Side effects of radiation therapy, Oral mucositis, cancer mouth sore.

 

Open-label study of 30 patients with painful lesions of the mouth and oropharynx associated with chemotherapy, radiation, mucositis, HIV disease, severe diffuse aphthous ulcers, or oral surgery.  Pain was scored on a Visual Numerical Scale ranging from 0 (no pain) to 10 (worst pain), with scores recorded at baseline and at 5 to 7 hours after treatment.  GELCLAIR® was administered TID.11

GELCLAIR® helps patients restore the ability to eat and drink more normally.11,12

Medium-term results
in the same open label study 87% of patients reported reduced pain associated with swallowing foods, liquids, and saliva after 7 days of use (p<0.005)11,12
Gelclair for: Mouth sores, Mouth ulcers, Chemotherapy side effects, Stomatitis, Magic mouthwash, Mucositis, mouth treatment ulcer, mouth lesions, Side effects of radiation therapy, Oral mucositis, cancer mouth sore.

GELCLAIR® helped reduce pain associated with eating and drinking.11,12

 Safety Profile

GELCLAIR® has a favorable safety profile:10

  • Generally well-tolerated

  • No known drug interactions

No adverse events have been reported in clinical trials with the use of GELCLAIR®. Postmarketing reports have included infrequent complaints of a burning sensation in the mouth. 

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Marketed and distributed by: EKR Therapeutics, Inc., Cedar Knolls, NJ 07927 under license of Helsinn Healthcare SA, Lugano, Switzerland
GELCLAIR® is a registered trademark of Helsinn Healthcare SA, Lugano, Switzerland.